After successful hepatitis C virus antiviral therapy: It looks that normal alanine aminotransferase level is not the normal
نویسندگان
چکیده
منابع مشابه
Clinical Features of Hepatitis C Virus Carriers With Persistently Normal Alanine Aminotransferase Levels
Hepatitis C virus (HCV) infection causes chronic hepatitis, which frequently leads to hepatic fibrosis and hepatocellular carcinoma (HCC). Alanine aminotransferase (ALT) is a biomarker of hepatocyte injury and is associated with the progression of hepatic fibrosis. Advanced hepatic fibrosis also predisposes HCV carriers to a risk of HCC. In contrast, some cases with persistent HCV infection hav...
متن کاملFrequency of hepatitis C viral RNA in anti-hepatitis C virus non- reactive blood donors with normal alanine aminotransferase.
OBJECTIVE To determine the frequency of HCV RNA in an anti-HCV non-reactive blood donor population with normal ALT, and its cost effectiveness. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Baqai Institute of Haematology, Baqai Medical University, Karachi, and Combined Military Hospital, Malir Cantt, Karachi, from May 2006 to April 2008. METHODOLOGY After initial interv...
متن کاملclinical features of hepatitis c virus carriers with persistently normal alanine aminotransferase levels
hepatitis c virus (hcv) infection causes chronic hepatitis, which frequently leads to hepatic fibrosis and hepatocellular carcinoma (hcc). alanine aminotransferase (alt) is a biomarker of hepatocyte injury and is associated with the progression of hepatic fibrosis. advanced hepatic fibrosis also predisposes hcv carriers to a risk of hcc. in contrast, some cases with persistent hcv infection hav...
متن کاملHistological and Clinical Characteristics of Patients with Chronic Hepatitis C and Persistently Normal Alanine Aminotransferase Levels
Patients with chronic hepatitis C virus (HCV) infection and persistently normal alanine aminotransferase (PNALT) are generally described to have mild liver disease. The aim of this study was to compare clinical and histological features in HCV-infected patients with PNALT and elevated ALT. Patients presenting to the University of Illinois Medical Center, Chicago, who had biopsy proven HCV, an A...
متن کاملPlasma Sphingolipids as Potential Indicators of Hepatic Necroinflammation in Patients with Chronic Hepatitis C and Normal Alanine Aminotransferase Level
Accurate estimation of hepatic necroinflammation caused by chronic hepatitis C (CHC) is crucial for prediction of prognosis and design of therapeutic strategy, which is particularly true for CHC patients with normal alanine aminotransferase (ALT) level. Recent studies have shown that sphingolipids have a close relationship with hepatitis C virus infection. The present study aimed to identify pl...
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ژورنال
عنوان ژورنال: Journal of Clinical Laboratory Analysis
سال: 2017
ISSN: 0887-8013
DOI: 10.1002/jcla.22296